Medications are available that can substantially delay ejaculation. The familiar 5-PDE inhibitors (Viagra, Levitra and Cialis) that are commonly used for erectile dysfunction, may have a role in the treatment of P.E. in men with acquired P.E. secondary to erectile dysfunction.

Anti-depressants of the S.S.R.I. class (selective serotonin reuptake inhibitors) have been clearly demonstrated to delay ejaculation. These medications can have undesirable side effects such as decreased libido, sleepiness, insomnia, headache, nausea and dry mouth. You are generally started on a low dose for two weeks with an increase in dose if necessary for the next two weeks. Once an effective dosage is achieved, you can use the medication on a situational basis, 3-4 hours prior to sexual intercourse.

The most commonly used medications are:

• Anafranil (Clomipramine): 25-50mg
• Paxil (Paroxetine): 20-40mg
• Zoloft (Sertraline): 25-100mg
• Prozac (Fluoxetine): 5-60mg

A new medication, Dapoxetine (30/60mg), is currently in investigational trials.

Insofar as most cases of P.E. have an underlying psychological basis, it may be beneficial to seek the aid of a sexual therapist who can help manage the problem with counseling sessions. This can be done in conjunction with some of the aforementioned techniques in order to bring about a quicker resolution.